PUBLICATIONS

2024年

Original Papers

  1. Pal, R.; Yamazaki, A.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Ando, H.
    Convergent synthesis of functionalized derivatives of stage-specific embryonic antigens 3 & 4
    Carbohydr. Res. 2024, 535, 108990.(2023/11/21)  DOI: 10.1016/j.carres.2023.108990 

Reviews and Commentaries

  1. Ando, H.; Komura, N.
    Recent progress in the synthesis of glycosphingolipids
    Curr. Opin. Chem. Biol. 2024, 78, 102423.(2024/1/6)  DOI: 10.1016/j.cbpa.2023.102423 

2023年

Original Papers

  1. Hagino, R.; Mozaki, K.; Komura, N.; Imamura, A.; Ishida, H.; Ando, H.; Tanaka, H.-N.
    Synthetic Approaches to Ribosyl Adenosine 5',5''-Diphosphate Fragment of Poly(ADP-ribose)
    Eur. J. Org. Chem. 2023, 26(41), e202300875.(2023/09/23)  DOI: 10.1002/ejoc.202300875 
  2. Asano, T.; Udagawa, T.; Komura, N.; Imamura, A.; Ishida, H.; Ando, H.; Tanaka, H.-N.
    Unprecedented neighboring group participation of C2 N-imidoxy functionalities for 1,2-trans-selective glycosylation
    Carbohydr Res. 2023, 527, 108808.(2023/04/06)  DOI: 10.1016/j.carres.2023.108808 
  3. Ikazaki, T.; Ishikawa, E.; Tamashima, H.; Akiyama, H.; Kimuro, Y.; Yoritate, M.; Matoba, H.; Imamura, A.; Ishida, H.; Yamasaki, S.; Hirai, G.
    Ligand-controlled stereoselective synthesis and biological activities of 2-exomethylene pseudo-glycoconjugates: Discovery of Mincle-selective ligands
    Angew. Chem. Int. Ed. 2023, 62, e202302569.(2023/04/02)  DOI: 10.1002/anie.202302569 
  4. Auger, A.; Yu, S. Y.; Guu, S. Y.; Quéméner, A.; Euller-Nicolas, G.; Ando, H.; Desdouits, M.; Le Guyader, F. S.; Khoo, K. H.; Le Pendu, J.; Chirat, F.; Guerardel, Y.
    Species-Specific N-Glycomes and Methylation Patterns of Oysters Crassostrea gigas and Ostrea edulis and Their Possible Consequences for the Norovirus–HBGA Interaction
    Mar. Drugs 2023, 21(6), 342.(2023/06/02)  DOI: 10.3390/md21060342 
  5. Murate, M.; Yokoyama, N.; Tomishige, N.; Richert, L.; Humbert, N.; Pollet, B.; Makino, A.; Kono, N.; Mauri, L.; Aoki, J.; Sako, Y.; Sonnino, S.; Komura, N.; Ando, H.; Kaneko, M. K.; Kato, Y.; Inamori, K. I.; Inokuchi, J. I.; Mély, Y.; Iwabuchi, K.; Kobayashi, T.
    Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells
    Cell. Mol. Life Sci. 2023, 80, 167.(2023/05/30)  DOI: 10.1007/s00018-023-04813-9 
  6. Suganuma, Y.; Imamura, A.; Ando, H.; Kiso, M.; Takematsu, H.; Tsubata, T.; Ishida, H.
    Improved synthesis of CD22‑binding sialosides and its application for further development of potent CD22 inhibitors
    Glycoconj. J. 2023, 40, 225–246.(2023/01/28)  DOI: 10.1007/s10719-023-10098-8 
  7. Yamaguchi, E.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Groux‑Degroote, S.; Mühlenhoff, M.; Suzuki, K. G. N.; Ando, H.
    Fluorescent GD2 analog for single‑molecule imaging
    Glycoconj. J. 2023, 40, 247–257.(2023/01/26)  DOI: 10.1007/s10719-023-10102-1 
  8. Hamajima, S.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Ichiyanagi, T.; Ando, H.
    Investigation of the Protection of the C4 Hydroxyl Group in Macrobicyclic Kdo Donors
    Molecules 2023, 28, 102.(2022/12/23)  DOI: 10.3390/molecules28010102 

Reviews and Commentaries

  1. Suzuki, K. G. N.; Komura, N.; Ando, H.
    Recently developed glycosphingolipid probes and their dynamic behavior in cell plasma membranes as revealed by single‑molecule imaging
    Glycoconj. J. 2023, 40, 305-314.(2023/5/3)  DOI: 10.1007/s10719-023-10116-9 
  2. Ando, H.
    Studies on the Drug Delivery Utilizing Glycan-protein Interactions(in Japanese)
    Drug. Deliv. Sys. 2023, 38, 305-312.(2023/12/25)  DOI: 10.2745/dds.38.305 

2022年

Original Papers

  1. Hamajima, S.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Noguchi, H.; Ichiyanagi, T.; Ando, H.
    Full stereocontrol in α-glycosidation of 3-deoxy-d-manno-2-octulosonic acid (Kdo) using macrobicyclic glycosyl donors
    Org. Lett. 2022, 24, 8672–8676.(2022/11/18)  DOI: 10.1021/acs.orglett.2c03542 
  2. Chantarasrivong, C.; Okuda, R.; Yamane, Y.; Yang, X.; Higuchi, Y.; Konishi, M.; Komura, N.; Ando, H.; Yokokawa, R; Yamashita, F.
    Disposition of E-selectin-targeting liposomes in tumor spheroids with a perfusable vascular network
    Drug Metab. Pharmacokinet. 2022, 47, 100469.(2022/8/7)  DOI: 10.1016/j.dmpk.2022.100469 
  3. Hagino, R.; Mozaki, K.; Komura, N.; Imamura, A.; Ishida, H.; Ando, H.; Tanaka, H.-N.
    Straightforward Synthesis of the Poly(ADP-ribose) Branched Core Structure
    ACS Omega. 2022, 7, 32795-32804.(2022/9/4)  DOI: 10.1021/acsomega.2c04732 
  4. Takahashi, M.; Komura, N.; Yoshida, Y.; Yamaguchi, E.; Hasegawa, A.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Suzuki, K. G. N.; Ando, H.
    Development of lacto-series ganglioside fluorescent probe using late-stage sialylation and behavior analysis with single-molecule imaging
    RSC Chem, Biol. 2022, 3, 868-885.  DOI: 10.1039/D2CB00083K 
  5. Hamaya, Y.; Komura, N.; Imamura, A.; Ishida, H.; Ando, H.; Tanaka, H.-N.
    Protecting-group- and microwave-free synthesis of β-glycosyl esters and aryl β-glycosides of N-acetyl-d-glucosamine
    Bioorg. Med. Chem. 2022, 67, 116852.(2022/8/1)  DOI: 10.1016/j.bmc.2022.116852 
  6. Vibhute, A. M.; Tanaka, H.-N.; Mishra, S. K.; Osuka, R. F.; Nagae, M.; Yonekawa, C.; Korekane, H.; Doerksen, R. J.; Ando, H.; Kizuka, Y.
    Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors
    BBA Gen. Sub. 2022, 1866, 130118.(2022/3/4)  DOI: 10.1016/j.bbagen.2022.130118 
  7. Araki, E.; Hane, M.; Hatanaka, R.; Kimura, R.; Tsuda, K.; Konisi, M.; Komura, N.; Ando, H.; Kitajima, K.;Sato, C.
    Analysis of biochemical features of ST8 α-N-acetyl-neuraminide α2,8-sialyltransferase (St8sia) 5 isoforms
    Glycoconjugate J. 2022, 39, 291–302.(2022/1/4)  DOI: 10.1007/s10719-021-10034-8 
  8. Ozaki, H.; Asano, T.; Tanaka, H.-N.; Komura, N.; Ando, H.; Ishida, H.; Imamura, A.
    Blockwise synthesis of polylactosamine fragments and keratan sulfate oligosaccharides comprised of dimeric Galβ(1→4)GlcNAc6Sβ
    Carbohydr. Res. 2022, 512, 108502.(2022/1/22)  DOI: 10.1016/j.carres.2022.108502 

Books

  1. Ando, H.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.
    Chemical synthesis of sialoglyco-architectures
    Adv. Carbohydr. Chem. Biochem. 2022, 81, 31-56.(2022/10/12)  DOI: 10.1016/bs.accb.2022.09.003 

2021年

Original Papers

  1. Hyun, S. W.; Imamura, A.; Ishida, H.; Piepenbrink, K. H.; Goldblum, S. E.; Lillehoj, E. P.
    The sialidase NEU1 directly interacts with the juxtamembranous segment of the cytoplasmic domain of mucin-1 to inhibit downstream PI3K-Akt signaling
    J. Biol. Chem. 2021, 297, 101337.(2021/10/22)  DOI: 10.1016/j.jbc.2021.101337 
  2. Fukuo, H.; Suzuki, T.; Shimabukuro, J.;Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Ando, H.
    Synthesis of Diverse Seleno-Glycolipids via the Transacetalization of Selenoacetals
    Eur. J. Org. Chem. 2021, 40, 5455-5467.(2021/8/11)  DOI: 10.1002/ejoc.202100847 (Front Cover)
  3. Alborzian Deh Sheikh, A.; Akatsu, C.; Abdu-Allah, H. H. M.; Suganuma, Y.; Imamura, A.; Ando, H.; Takematsu, H.; Ishida, H.; Tsubata, T.
    The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells
    J. Immunol. 2021, 206, 2544-2551. (2021/06/01)  DOI: 10.4049/jimmunol.2100109 
  4. Nakano, M.; Hanashima, S.; Hara, T.; Kabayama, K.; Asahina, Y.; Hojo, H.; Komura, N.; Ando, H.; Nyholm, T. K. M.; Slotte, J. P.; Murata, M.
    FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers
    Biochim. Biophys. Acta. Biomembr. 2021, 1863, 183623. (2021/04/05)  DOI: 10.1016/j.bbamem.2021.183623 
  5. Nagata, M.; Toyonaga, K.; Ishikawa, E.; Haji, S.; Okahashi, N.; Takahashi, M.; Izumi, Y.; Imamura, A.; Takato, K.; Ishida, H.; Nagai, S.; Illarionov, P.; Stocker, B. L.; Timmer, M. S. M.; Smith, D. G. M.; Williams, S. J.; Bamba, T.; Miyamoto, T.; Arita, M.; Appelmelk, B. J.; Yamasaki, S.
    Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors
    J. Exp. Med. 2021, 218, 1. (2021/01/04)  DOI: 10.1084/jem.20200815 
  6. Nakato, M.; Shiranaga, N.; Tomioka, M.; Watanabe, H.; Kurisu, J.; Kengaku, M.; Komura, N.; Ando, H.; Kimura, Y.; Kioka, N.; Ueda, K.
    ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking
    J. Biol. Chem. 2021, 296, 100166. (2021/01/04)  DOI: 10.1074/jbc.RA120.015997 
  7. Luzina, I. G.; Lillehoj, E. P.; Lockatell, V.; Hyun, S. W.; Lugkey, K. N.; Imamura, A.; Ishida, H.; Cairo, C. W.; Atamas, S. P.; Goldblum, S. E.
    Therapeutic Effect of Neuraminidase-1–Selective Inhibition in Mouse Models of Bleomycin-Induced Pulmonary Inflammation and Fibrosis
    J. Pharmacol. Exp. Ther. 2021, 376, 136-146. (2021/01/01)  DOI: 10.1124/jpet.120.000223 

Reviews and Commentaries

  1. 石田秀治
    糖質と疾患の化学
    CSJ Current Review 39: 生体分子と疾患, pp.22-25.(2021/8/25) 
  2. 安藤弘宗
    架橋糖のグリコシル化
    月刊BIOINDUSTRY 2021, 38 , 54-63.(2021/8/12) 
  3. Vibhute, A. M.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ando, H.
    Advanced Chemical Methods for Stereoselective Sialylation and Their Applications in Sialoglycan Syntheses
    Chem. Rec. 2021, 21, 1-31.(2021/5/24)  DOI: 10.1002/tcr.202100080 

2020年

  1. Yagami, N.;  Vibhute, A. M.;  Tanaka, H.-N.;  Komura, N.;  Imamura, A.;  Ishida, H.;  Ando, H.
    Stereoselective Synthesis of Diglycosyl Diacylglycerols with Glycosyl Donors Bearing a β-Stereodirecting 2,3-Naphthalenedimethyl Protecting Group
    J. Org. Chem. 2020, 85, 16166–16181. (2020/11/30)  DOI: 10.1021/acs.joc.0c02121 
  2. Konishi, M.; Komura, N.; Hirose, Y.; Suganuma, Y.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Suzuki, K. G. N.; Ando, H.
    Development of fluorescent ganglioside GD3 and GQ1b analogs for elucidation of raft-associated interactions
    J. Org. Chem. 2020, 85, 15998–16013. (2020/09/21)  DOI: 10.1021/acs.joc.0c01493 
  3. Tomida, H.; Matsuhashi, T.; Tanaka, H.-N.; Komura, N. ; Ando, H.; Imamura, A.; Ishida, H.
    Indirect synthetic route to α-l-fucosides via highly stereoselective construction of α-l-galactosides followed by C6-deoxygenation
    Org. Biomol. Chem. 2020, 18, 5017–5033. (2020/06/18)
  4. Nobeyama, T.; Shigyou, K.; Nakatsuji, H.; Sugiyama, H.; Komura, N.; Ando, H.; Hamada, T.; Murakami, T.
    Control of lipid bilayer phases of cell-sized liposomes by surface-engineered plasmonic nanoparticles
    Langmuir 2020, 36 , 7741–7746. (2020/06/05)
  5. Kanoh, H.; Nitta, T.; Go, S.; Inamori, K. I.; Veillon, L.; Nihei, W.; Fujii, M.; Kabayama, K.; Shimoyama, A.; Fukase, K.; Ohto, U.; Shimizu, T.; Watanabe, T.; Shindo, H.; Aoki, S.; Sato, K.; Nagasaki, M.; Yatomi, Y.; Komura, N.; Ando, H.; Ishida, H.; Kiso, M.; Natori, Y.; Yoshimura, Y.; Zonca, A.; Cattaneo, A.; Letizia, M.; Ciampa, M.; Mauri, L.; Prinetti, A.; Sonnino, S.; Suzuki, A.; Inokuchi, J. I.
    Homeostatic and pathogenic roles of GM 3 ganglioside molecular species in TLR 4 signaling in obesity
    EMBO J. 2020, 39, e101732. (2020/05/07)
  6. Shirasaki, J.; Tanaka, H.-N.; Konishi, M.; Hirose, Y.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.
    Systematic strategy utilizing 1,5-lactamization for the synthesis of the trisialylated galactose unit of c-series gangliosides
    Tetrahedron Lett. 2020, 61, 151759. (2020/04/16)
  7. Takahashi, M.; Shirasaki, J.; Komura, N.; Sasaki, K.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Hanashima, S.; Murata, M.; Ando, H.
    Efficient diversification of GM3 gangliosides via late-stage sialylation and dynamic glycan structural studies with 19F solid-state NMR
    Org. Biomol. Chem. 2020, 18, 2902–2913. (2020/03/23)
  8. Omahdi, Z.; Horikawa, Y.; Nagae, M.; Toyonaga, K.; Imamura, A.; Takato, K.; Teramoto, T.;
    Ishida, H.; Kakuta, Y.; Yamasaki, S.
    Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR
    J. Biol. Chem. 2020, 295, 5807–5817. (2020/03/05)
  9. Komura, N.
    Novel glycosidation based on alkyne activation (GLYCOTOPIC)
    Trends Glycosci. Glycotechnol. 2020, 32, E35–E36. (2020/01/25)
  10. Yanaka, S.; Yogo, R.; Watanabe, H.; Taniguchi, Y.; Satoh, T.; Komura, N.; Ando, H.; Yagi, H.;
    Yuki, N.;  Uchihashi, T.; Kato, K.
    On-membrane dynamic interplay between anti-GM1 IgG antibodies and complement component C1q
    Int. J. Mol. Sci. 2020, 21, 147. (2019/12/24)
  11. Kusumi, A.; Fujiwara, T. K.; Tsunoyama, T. A.; Kasai, R. S.; Liu, A. A.; Hirosawa, K. M.;
    Kinoshita, M.;  Matsumori, N.; Komura, N.; Ando, H.; Suzuki, K. G. N.
    Defining raft domains in the plasma membrane
    Traffic 2020, 21, 106–137. (2019/11/24)

2019年

  1. Asano, S.; Pal, R.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Suzuki, K. G. N.; Ando, H.
    Development of fluorescently labeled SSEA-3, SSEA-4, and Globo-H glycosphingolipids for elucidating molecular interactions in the cell membrane
    Int. J. Mol. Sci. 2019, 20, 6187. (2019/12/07)
  2. Takato, K.; Kurita, M.; Yagami, N.; Tanaka, H.-N.; Ando, H.; Imamura, A.; Ishida, H.
    Chemical synthesis of diglucosyl diacylglycerols utilizing glycosyl donors with stereodirecting cyclic silyl protective groups
    Carbohydr. Res. 2019, 483, 107748. (2019/09/01)
  3. Nagata, S.; Tomida, H.; Iwai-Hirose, H.; Tanaka, H.-N.; Ando, H.; Imamura, A.; Ishida, H.
    Synthesis of a 1,2-cis-indoxyl galactoside as a chromogenic glycosidase substrate
    RSC Advances 2019, 9, 28241–28247. (2019/09/09)
  4. Suzuki, T.; Hayashi, C.; Komura, N.; Tamai, R.; Uzawa, J.; Ogawa, J.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Kiso, M.; Yamaguchi, Y.; Ando, H.
    Synthesis and glycan–protein interaction studies of Se-Sialosides by 77Se NMR
    Org. Lett. 2019, 21, 6393–6396. (2019/08/08)
  5. Chantarasrivong, C.; Higuchi, Y.; Tsuda, M.; Yamane, Y.; Hashida, M.; Konishi, M.; Komura, N.; Ando, H.; Yamashita, F.
    Sialyl LewisX mimic-decorated liposomes for anti-angiogenic everolimus delivery to E-selectin expressing endothelial cells
    RSC Advances 2019, 9, 20518–20527. (2019/07/02)
  6. Asano, S.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Ando, H.
    p-tert-Butyl groups improve the utility of aromatic protecting groups in carbohydrate synthesis
    Org. Lett. 2019, 21, 4197–4200. (2019/05/30)
  7. Koikeda, M.; Komura, N.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.
    Synthesis of ganglioside analogs containing fluorescently labeled GalNAc for single-molecule imaging
    J. Carbohydr. Chem. 2019, 38, 509–527. (2019/05/27)
  8. Goto, K.; Tamai, H.; Takeda, Y.; Tanaka, H.-N.; Mizuno, T.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.
    Total synthesis of sialyl inositol phosphosphingolipids CJP-2, CJP-3, and CJP-4 isolated from feather star Comanthus japonica
    Org. Lett. 2019, 21, 4054–4057. (2019/05/22)
  9. Komura, N.; Kato, K.; Udagawa, T.; Asano, S.; Tanaka, H.-N.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.
    Constrained sialic acid donors enable selective synthesis of α-glycosides
    Science 2019, 364, 677–680. (2019/05/17)
  10. Tanaka, H.
    Recent developments of protecting-group-free and stereoselective glycosylation (review de debut)
    J. Synth. Org. Chem. Jpn. 2019, 77, 365–366. (2019/04/01)
  11. Tanaka, H.
    Carbon–carbon bond formation at the reducing end of uprotected oligosaccharides (GLYCOTOPIC)
    Trends Glycosci. Glycotechnol. 2019, 31, E31–E32. (2019/01/25)
  12. Lillehoj, E. P.; Guang, W.; Hyun, S. W.; Liu, A.; Hegerle, N.; Simon, R.; Cross, A. S.; Ishida, H.; Luzina, I. G.; Atamas, S. P.; Goldblum, S. E.
    Neuraminidase 1–mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection
    J. Biol. Chem. 2019, 294, 662–678. (2018/11/14)
  13. Yoshida, F.; Yoshinaka, H.; Tanaka, H.; Hanashima, S.; Yamaguchi, Y.; Ishihara, M.;
    Saburomaru, M.;  Kato, Y.; Saito, R.; Ando, H.; Kiso, M.; Imamura, A.; Ishida, H.
    Synthesis of the core oligosaccharides of lipooligosaccharides from Campylobacter jejuni : a putative cause of Guillain–Barré syndrome
    Chem. Eur. J. 2019, 25, 796–805. (2018/10/18)

2018年

  1. Imai, T.; Matsumura, T.; Mayer-Lambertz, S.; Wells, C. A.; Ishikawa, E.; Butcher, S. K.;
    Barnett, T. C.;  Walker, M. J.; Imamura, A.; Ishida, H.; Ikebe, T.; Miyamoto, T.; Ato, M.; Ohga, S.; Lepenies, B.; Van Sorge, N. M.; Yamasaki, S.
    Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection
    Proc. Natl. Acad. Sci. U. S. A. 2018, 115, E10662–E10671. (2018/10/23)
  2. Matsubara, N.; Imamura, A.; Yonemizu, T.; Akatsu, C.; Yang, H.; Ueki, A.; Watanabe, N.;
    Abdu-Allah, H. H. M.; Numoto, N.; Takematsu, H.; Kitazume, S.; Tedder, T. F.; Marth, J. D.;Ito, N.; Ando, H.; Ishida, H.;  Kiso, M.; Tsubata, T.
    CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice
    Front. Immunol. 2018, 9, 820. (2018/04/19)
  3. Kijimoto-Ochiai, S.; Matsumoto-Mizuno, T.; Kamimura, D.; Murakami, M.; Kobayashi, M.; Matsuoka, I.; Ochiai, H.; Ishida, H.; Kiso, M.; Kamimura, K.; Koda, T.
    Existence of NEU1 sialidase on mouse thymocytes whose natural substrate is CD5
    Glycobiology 2018, 28, 306–317. (2018/01/30)
  4. Tanaka, H.; Hamaya, Y.; Nishiwaki, N.; Ishida, H.
    A concise synthesis of rhamnan oligosaccharides with alternating α-(1→2)/(1→3)-linkages and repeating α-(1→3)-linkages by iterative α-glycosylation using disaccharide building blocks
    Carbohydr. Res. 2018, 455, 23–31. (2018/01/02)
  5. Alborzian Deh Sheikh, A.; Akatsu, C.; Imamura, A.; Abdu-Allah, H. H. M.; Takematsu, H.;
    Ando, H.; Ishida, H.; Tsubata, T.
    Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions
    Biochem. Biophys. Res. Commun. 2018, 495, 854–859. (2017/11/14)
  6. Suzuki, K. G. N.; Ando, H.; Komura, N.; Konishi, M.; Imamura, A.; Ishida, H.; Kiso, M.;
    Fujiwara, T. K.; Kusumi, A.
    Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs
    Methods Enzymol. 2018, 598, 267–282. (2017/10/31)

2017年

  1. Tanase, M.; Imamura, A.; Ando, H.; Kiso, M.; Ishida, H.
    Linear synthesis of the Chol-1 ganglioside core tetrasaccharide and disialyl T antigen glycan using a 5-ureido-sialyl donor
    Biosci. Biotechnol. Biochem. 2017, 81, 2268–2278. (2017/11/08)
  2. Ando, H.; Komura, N.; Imamura, A.; Kiso, M.; Ishida, H.
    A Synthetic Challenge to the Diversity of Gangliosides for Unveiling Their Biological Significance
    J. Synth. Org. Chem. Jpn. 2017, 75, 1162–1170. (2017/11/01)
  3. Suzuki, K. G. N.; Ando, H.; Komura, N.; Fujiwara, T. K.; Kiso, M.; Kusumi, A.
    Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging
    Biochim. Biophys. Acta Gen. Subj. 2017, 1861, 2494–2506. (2017/07/20)
  4. Komura, N.; Suzuki, K. G. N.; Ando, H.; Konishi, M.; Imamura, A.; Ishida, H.; Kusumi, A.;
    Kiso, M.
    Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains
    Methods Enzymol. 2017, 597, 239–263. (2017/07/18)
  5. Yagami, N.; Tamai, H.; Udagawa, T.; Ueki, A.; Konishi, M.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.
    A 1,2-trans-Selective Glycosyl Donor Bearing Cyclic Protection at the C-2 and C-3 Hydroxy Groups
    Eur. J. Org. Chem. 2017, 4778–4785. (2017/07/17)
  6. Chantarasrivong, C.; Ueki, A.; Ohyama, R.; Unga, J.; Nakamura, S.; Nakanishi, I.; Higuchi, Y.;  Kawakami, S.; Ando, H.; Imamura, A.; Ishida, H.; Yamashita, F.; Kiso, M.; Hashida, M.
    Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells
    Mol. Pharm. 2017, 14, 1528–1537. (2017/02/13)
  7. Shimabukuro, J.; Makyio, H.; Suzuki, T.;Nishikawa, Y.; Kawasaki, M.; Imamura, A.; Ishida, H.; Ando, H.; Kato, R.; Kiso, M.
    Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing
    Bioorg. Med. Chem. 2017, 25, 1132–1142. (2017/02/01)
  8. Komura, N.; Yamazaki, A.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.
    Syntheses of bifunctional photoaffinity ganglioside probes for studying raft-​associated interactions
    Trends Carbohydr. Res. 2017, 9, 1–26. (2017/01)

2016年

  1. Imamura, A.; Matsuzawa, N.; Sakai, S.; Udagawa, T.; Nakashima, S.; Ando, H.; Ishida, H.; Kiso, M.
    The Origin of High Stereoselectivity in Di-tert-butylsilylene-Directed α-Galactosylation
    J. Org. Chem. 2016, 81, 9086–9104. (2016/09/20)
  2. Hyun, S. W.; Liu, A.; Liu, Z.; Cross, A. S.;Verceles, A. C.; Sadagopan, M.; Kommagalla, Y.;
    Kona, C.; Ando, H.; Luzina, I. G.; Atamas, S. P.; Piepenbrink, K. H.; Sundberg, E. J.; Guang, W.; Ishida, H.; Lillehoj, E. P.; Goldblum, S. E.
    The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo
    Glycobiology 2016, 26, 834–849. (2016/09/02)
  3. Makyio, H.; Shimabukuro, J.; Suzuki, T.; Imamura, A.; Ishida, H.; Kiso, M.; Ando, H.; Kato, R.
    Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin
    Biochem. Biophys. Res. Commun. 2016, 477, 477–482. (2016/06/16)
  4. Goto, K.; Sawa, M.; Tamai, H.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    The Total Synthesis of Starfish Ganglioside GP3 Bearing a Unique Sialyl Glycan Architecture
    Chem. Eur. J. 2016, 22, 8323–8331. (2016/05/12)
  5. Kobayashi, D.; Ueki, A.; Yamaji, T.; Nagao, K.; Imamura, A.; Ando, H.; Kiso, M.; Ishida, H.
    Efficient Synthesis of the Lewis A Tandem Repeat
    Molecules 2016, 21, 614. (2016/05/11)
  6. Sriwilaijaroen, N.; Sadagopan, M.; Imamura, A.; Ando, H.; Ishida, H.; Sakai, M.; Ishitsubo, E.;
    Hori, T.;  Moriya, S.; Ishikawa, T.; Kuwata, K.; Odagiri, T.; Tashiro, M.; Hiramatsu, H.; Tsukamoto, K.; Miyagi, T.; Tokiwa, H.; Kiso, M.; Suzuki, Y.
    A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1–N9 Neuraminidases: Insight into Neuraminidase–Inhibitor Interactions
    J. Med. Chem. 2016, 59, 4563–4577. (2016/04/20)
  7. Komura, N.; Suzuki, K. G.; Ando, H.; Konishi, M.; Koikeda, M.; Imamura, A.; Chadda, R.; Fujiwara, T. K.; Tsuboi, H.; Sheng, R.; Cho, W.; Furukawa, K.; Furukawa, K.; Yamauchi, Y.; Ishida, H.; Kusumi, A.; Kiso, M.
    Raft-based interactions of gangliosides with a GPI-anchored receptor
    Nat. Chem. Biol. 2016, 12, 402–410. (2016/04/04)
  8. Tanase, M.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    A 5-Ureido-Modified Sialyl Donor: A Tool for the Synthesis of α-Sialosides
    Org. Lett. 2016, 18, 1454–1457. (2016/03/03)

2015年

  1. Yamagishi, M.; Hosoda-Yabe, R.; Tamai, H.; Konishi, M.; Imamura, A.; Ishida, H.; Yabe, T.;
    Ando, H.; Kiso, M.
    Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3
    Mar. Drugs 2015, 13, 7250–7274. (2015/12/05)
  2. Hirose, H.; Tamai, H.; Gao, C.; Imamura, A.; Ando, H.; Ishida, H.; Feizi, T.; Kiso, M.
    Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a
    Org. Biomol. Chem. 2015, 13, 11105–11117. (2015/09/24)
  3. Goto, K.; Suzuki, T.; Tamai, H.; Ogawa, J.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Total Synthesis and Neuritogenic Activity Evaluation of Ganglioside PNG-2A from the Starfish Protoreaster nodosus
    Asian J. Org. Chem. 2015, 4, 1160–1171. (2015/09/07)
  4. Tamai, H.; Imamura, A.; Ogawa, J.; Ando, H.; Ishida, H.; Kiso, M.
    First Total Synthesis of Ganglioside GAA-7 from Starfish Asterias amurensis versicolor
    Eur. J. Org. Chem. 2015, 5199–5211. (2015/07/08)
  5. Ueki, A.; Un, K.; Mino, Y.; Yoshida, M.; Kawakami, S.; Ando, H.; Ishida, H.; Yamashita, F.; Hashida, M.; Kiso, M.
    Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems
    Carbohydr. Res. 2015, 405, 78–86. (2015/03/20)
  6. Sumida, M.; Hane, M.; Yabe, U.; Shimoda, Y.; Pearce, O. M.; Kiso, M.; Miyagi, T.; Sawada, M.; Varki, A.; Kitajima, K.; Sato, C.
    Rapid Trimming of Cell Surface Polysialic Acid (PolySia) by Exovesicular Sialidase Triggers Release of Preexisting Surface Neurotrophin
    J. Biol. Chem. 2015, 290, 13202–13214. (2015/03/06)
  7. Ando, H.
    Synthetic approach toward complexity of sialic acid-containing glycans
    Biosci. Biotechnol. Biochem.2015, 79, 343–346. (2014/12/11)
  8. Yabe, T.; Hosoda-Yabe, R.; Sakai, H.; Kanamaru, Y.; Kiso, M.
    Development of a photoreactive probe-based system for detecting heparin
    Anal. Biochem. 2015, 472, 1–6. (2014/11/20)
  9. Abe, S.; Tokura, Y.; Pal, R.; Komura, N.; Imamura, A.; Matsumoto, K.; Ijiri, H.;
    Sanghamitra, N. J. M.;  Tabe, H.; Ando, H.; Kiso, M.; Mori, H.; Kitagawa, S.; Ueno, T.
    Surface Functionalization of Protein Crystals with Carbohydrate Using Site-selective Bioconjugation
    Chem. Lett. 2015, 44, 29–31. (2014/10/11)
  10. Ohnuma, A.; Nagata, T.; Komura, K.; Ando, H.; Ishihara, H.; Koketsu, M.
    Preparation of 2H-5,6-Dihydroselenines Using α-Alkoxy Carbonylselenoacetamide
    J. Heterocycl. Chem. 2015, 52, 513–517. (2014/05/26)

2014年

  1. Kiso, M.; Ando, H.; Menjo, M.; Tamai, H.; Ishida, H.; Koketsu, M.
    Glycosidation Reactions of Benzyl-Type Selenoglycoside Donors
    Heterocycles 2014, 88,1587–1594. (2013/09/30)
  2. Imamura, A.
    What Is the Source of Stereoselectivity in Cyclic Silyl-Protected Glycosyl Donor System? (GLYCOTOPIC)
    Trends Glycosci. Glycotechnol. 2014, 26, 141–143. (2014/09/25)
  3. Kitazume, S.; Imamaki, R.; Kurimoto, A.; Ogawa, K.; Kato, M.; Yamaguchi, Y.; Tanaka, K.;
    Ishida, H.;  Ando, H.; Kiso, M.; Hashii, N.; Kawasaki, N.; Taniguchi, N.
    Interaction of Platelet Endothelial Cell Adhesion Molecule (PECAM) with α2,6-Sialylated Glycan Regulates Its Cell Surface Residency and Anti-apoptotic Role
    J. Biol. Chem. 2014, 289, 27604–27613. (2014/08/18)
  4. Suzuki, T.; Makyio, H.; Ando, H.; Komura, N.; Menjo, M.; Yamada, Y.; Imamura, A.; Ishida, H.;  Wakatsuki, S.; Kato, R.; Kiso, M.
    Expanded potential of seleno-carbohydrates as a molecular tool for X-ray structural determination of a carbohydrate–protein complex with single/multi-wavelength anomalous dispersion phasing
    Bioorg. Med. Chem. 2014, 22, 2090–2101. (2014/04/01)
  5. Suzuki, T.; Komura, N.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    A facile method for synthesizing selenoglycosides based on selenium-transfer to glycosyl imidate
    Tetrahedron Lett. 2014, 55, 1920–1923. (2014/03/12)
  6. Hara, A.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    A New Chemical Approach to Human ABO Histo-Blood Group Type 2 Antigens
    Molecules 2014, 19, 414–437. (2013/12/31)

2013年

  1. Konishi, M.; Imamura, A.; Fujikawa, K.; Ando, H.; Ishida, H.; Kiso, M.
    Extending the Glucosyl Ceramide Cassette Approach: Application in the Total Synthesis of Ganglioside GalNAc-GM1b
    Molecules 2013, 18, 15153–15181. (2013/12/10)
  2. Crusat, M.; Liu, J.; Palma, A. S.; Childs, R. A.; Liu, Y.; Wharton, S. A.; Lin, Y. P.; Coombs, P. J.; Martin, S. R.; Matrosovich, M.; Chen, Z.; Stevens, D. J.; Hien, V. M.; Thanh, T. T.; Nhu, L. N. T.; Nguyet, L. A.;  Ha, D. Q.; van Doorn, H. R.; Hien, T. T.; Conradt, H. S.; Kiso, M.; Gamblin, S. J.; Chai, W.; Skehel, J. J.; Hay, A. J.; Farrar, J.; de Jong, M. D.; Feizi, T.
    Changes in the hemagglutinin of H5N1 viruses during human infection – Influence on receptor binding
    Virology 2013, 447, 326–337. (2013/09/17)
  3. Yamada, Y.; Kobayashi, H.; Iwasa, M.; Sumi, S.; Ushikoshi, H.; Aoyama, T.; Nishigaki, K.; Takemura, G.; Fujiwara, T.; Fujiwara, H.; Kiso, M.; Minatoguchi, S.
    Postinfarct active cardiac-targeted delivery of erythropoietin by liposomes with sialyl Lewis X repairs infarcted myocardium in rabbits
    Am. J. Physiol. Heart Circ. Physiol. 2013, 304, H1124–H1133. (2013/04/15)
  4. Kasai, T.; Nakane, D.; Ishida, H.; Ando, H.; Kiso, M.; Miyata, M.
    Role of Binding in Mycoplasma mobile and Mycoplasma pneumoniae Gliding Analyzed through Inhibition by Synthesized Sialylated Compounds
    J. Bacteriol. 2013, 195, 429–435. (2013/01/14)

2012年

  1. Tamai, H.; Ando, H.; Ishida, H.; Kiso, M.
    First Synthesis of a Pentasaccharide Moiety of Ganglioside GAA-7 Containing Unusually Modified Sialic Acids through the Use of N-Troc-sialic Acid Derivative as a Key Unit
    Org. Lett. 2012, 14, 6342–6345. (2012/12/10)
  2. Nohara, T.; Imamura, A.; Yamaguchi, M.; Hidari, K. I.; Suzuki, T.; Komori, T.; Ando, H.; Ishida, H.; Kiso, M.
    Design and Synthesis of a Novel Ganglioside Ligand for Influenza A Viruses
    Molecules 2012, 17, 9590–9620. (2012/08/10)
  3. Neu, U.; Hengel, H.; Blaum, B. S.; Schowalter, R. M.; Macejak, D.; Gilbert, M.; Wakarchuk, W. W.;  Imamura, A.; Ando, H.; Kiso, M.; Arnberg, N.; Garcea, R. L.; Peters, T.; Buck, C. B.; Stehle, T.
    Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection
    PLoS Pathog. 2012, 8, e1002738. (2012/07/26)
  4. Tako, M.; Dobashi, Y.; Tamaki, Y.; Konishi, T.; Yamada, M.; Ishida, H.; Kiso, M.
    Identification of rare 6-deoxy-d-altrose from an edible mushroom (Lactarius lividatus)
    Carbohydr. Res. 2012, 350, 25–30. (2012/03/01)
  5. Nakashima, S.; Ando, H.; Saito, R.; Tamai, H.; Ishida, H.; Kiso, M.
    Efficiently Synthesizing Lacto-Ganglio-Series Gangliosides by Using a Glucosyl Ceramide Cassette Approach: The Total Synthesis of Ganglioside X2
    Chem. Asian J. 2012, 7, 1041–1051. (2012/02/12)

2011年

  1. Shimizu, H.; Iwayama, Y.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Synthesis of the Disialic Acid-Embedded Glycan Part of Ganglioside HPG-1
    Biosci. Biotech. Biochem. 2011, 75, 2079–2082. (Accepted: 2011/08/29)
  2. Abdu-Allah, H. H. M.; Watanabe, K.; Daikoku, S.; Kanie, O.; Tsubata, T.; Ando, H.; Ishida, H.; Kiso, M.
    Design and Synthesis of a Multivalent Heterobifunctional CD22 Ligand as a Potential Immunomodulator
    Synthesis 2011, 2011, 2968–2974. (2011/08/05)
  3. Imamura, A.; Lowary, T.
    Chemical Synthesis of Furanose Glycosides
    Trends Glycosci. Glycotechnol. 2011, 23, 134–152. (2011/07/28)
  4. Iwayama, Y.; Ando, H.; Tanaka, H.-N.; Ishida, H.; Kiso, M.
    Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue
    Chem. Commun. 2011, 47, 9726–9728. (2011/07/21)
  5. Fujikawa, K.; Nakashima, S.; Konishi, M.; Fuse, T.; Komura, N.; Ando, T.; Ando, H.; Yuki, N.; Ishida, H.; Kiso, M.
    The First Total Synthesis of Ganglioside GalNAc-GD1a, a Target Molecule for Autoantibodies in Guillain–Barré Syndrome
    Chem. Eur. J. 2011, 17, 5641–5651. (2011/04/05)
  6. Abdu-Allah, H. H. M.; Watanabe, K.; Completo, G. C.; Sadagopan, M.; Hayashizaki, K.;
    Takaku, C.;  Tamanaka, T.; Takematsu, H.; Kozutsumi, Y.; Paulson, J. C.; Tsubata, T.; Ando, H.; Ishida, H.; Kiso, M.
    CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold
    Bioorg. Med. Chem. 2011, 19, 1966–1971. (2011/03/15)
  7. Tamai, H.; Ando, H.; Tanaka, H.-N.; Hosoda-Yabe, R.; Yabe, T.; Ishida, H.; Kiso, M.
    The Total Synthesis of the Neurogenic Ganglioside LLG-3 Isolated from the Starfish Linckia laevigata
    Angew. Chem. Int. Ed. 2011, 50, 2330–2333. (2011/02/24)
  8. Yabe, T.; Hosoda-Yabe, R.; Kanamaru, Y.; Kiso, M.
    A Peptide Found by Phage Display Discriminates a Specific Structure of a Trisaccharide in Heparin
    J. Biol. Chem. 2011, 286, 12397–12406. (2011/02/18)
  9. Sadagopan, M.; Sriwilaijaroen, N.; Moriya, S.; Ando, H.; Miyagi, T.; Suzuki, Y.; Ishida, H.;  Kiso, M.
    Evaluation of a Set of C9 N-acyl Neu5Ac2en Mimetics as Viral Sialidase Selective Inhibitors
    Int. J. Med. Chem. 2011, 2011, 539245. (2010/12/28)
  10. Nakashima, S.; Ando, H.; Imamura, A.; Yuki, N.; Ishida, H.; Kiso, M.
    A First Total Synthesis of a Hybrid-Type Ganglioside Associated with Amyotrophic Lateral Sclerosis-Like Disorder
    Chem. Eur. J. 2011, 17, 588–597. (2010/11/05)
  11. Yamada, M.; Yoshida, F.; Ando, H.; Ishida, H.; Kiso, M.; Tako, M.
    Synthesis of 6-Deoxy-d-altrose Used as an Authentic Sample to Identify an Unknown Monosaccharide Isolated from the Fruiting Body of an Edible Mushroom
    Heterocycles 2011, 82, 1699–1704. (2010/08/26)

2010年

  1. Friedrich, N.; Santos, J. M.; Liu, Y.;Palma, A. S.; Leon, E.; Saouros, S.; Kiso, M.; Blackman, M. J.;  Matthews, S.; Feizi, T.; Soldati-Favre, D.
    Members of a Novel Protein Family Containing Microneme Adhesive Repeat Domains Act as Sialic Acid-binding Lectins during Host Cell Invasion by Apicomplexan Parasites
    J. Biol. Chem. 2010, 285, 2064–2076. (2010/11/09)
  2. Liu, Y.; Childs, R. A.; Matrosovich, T.; Wharton, S.; Palma, A. S.; Chai, W.; Daniels, R.; Gregory, V.;  Uhlendorff, J.; Kiso, M.; Klenk, H.-D.; Hay, A.; Feizi, T.; Matrosovich, M.
    Altered Receptor Specificity and Cell Tropism of D222G Hemagglutinin Mutants Isolated from Fatal Cases of Pandemic A(H1N1) 2009 Influenza Virus
    J. Virol. 2010, 84, 12069–12074. (2010/10/25)
  3. Ando, H.; Ishida, H.; Kiso, M.
    Renewed Synthetic Approach to Gangliosides Exploiting Versatile and Powerful Synthetic Units
    Methods Enzymol. 2010, 598, 521–540. (2010/09/03)
  4. Sadagopan, M.; Sriwilaijaroen, N.; Savita, V.; Ando, H.; Miyagi, T.; Suzuki, Y.; Ishida, H.; Kiso, M.
    Investigation of 2-Fluoro Benzoic Acid Derivatives as Influenza A Viral Sialidase Selective Inhibitors
    Antiinfect. Agents Med. Chem. 2010, 9, 198–204. (2010/09-12)
  5. Yamanaka, T.; Tsujimura, K.; Kondo, T.; Matsumura, T.; Ishida, H.; Kiso, M.; Hidari, K. I. P. ; Suzuki, T.
    Infectivity and pathogenicity of canine H3N8 influenza A virus in horses
    Influenza Other Respir. Viruses 2010, 4, 345–351. (2010/07/28)
  6. Fujikawa, K.; Nohara, T.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    A cyclic glucosyl ceramide acceptor as a versatile building block for complex ganglioside synthesis
    Tetrahedron Lett. 2010, 51, 1126–1130. (2010/02/17)
  7. Sadagopan, M.; Moriya, S.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
    Use of structure-based virtual screening in the investigation of novel human sialidase inhibitors
    Med. Chem. Res. 2010, 19, 1273–1286. (2009/10/14)

2009年

  1. Abdu-Allah, H. H. M.; Watanabe, K.; Hayashizaki, K.; Takaku, C.; Tamanaka, T.; Takematsu, H.;  Kozutsumi, Y.; Tsubata, T.; Ishida, H.; Kiso, M.
    Potent small molecule mouse CD22-inhibitors: Exploring the interaction of the residue at C-2 of sialic acid scaffold
    Bioorg. Med. Chem. Lett. 2009, 19, 5573–5575. (2009/10/01)
  2. Takahashi, T.; Hashimoto, A.; Maruyama, M.; Ishida, H.; Kiso, M.; Kawaoka, Y.; Suzuki, Y.; Suzuki, T.
    Identification of amino acid residues of influenza A virus H3 HA contributing to the recognition of molecular species of sialic acid
    FEBS Lett. 2009, 583, 3171–3174. (2009/09/29)
  3. Childs, R. A.; Palma, A. S.; Wharton, S.; Matrosovich, T.; Liu, Y.; Chai, W.; Campanero-Rhodes, M. A.;  Zhang, Y.; Eickmann, M.; Kiso, M.; Hay, A.; Matrosovich, M.; Feizi, T.
    Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray
    Nat. Biotechnol. 2009, 27, 797–799. (2009/09)
  4. Komori, T.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates
    Carbohydr. Res. 2009, 344, 1453–1463. (2009/08/17)
  5. Abdu-Allah, H. H. M.; Watanabe, K.; Hayashizaki, K.; Iwayama, Y.; Takematsu, H.; Kozutsumi, Y.;  Tsubata, T.; Ishida, H.; Kiso, M.
    Synthesis of biotinylated sialoside to probe CD22–ligand interactions
    Tetrahedron Lett. 2009, 50, 4488–4491. (2009/08/05)
  6. Tanaka, H.; Ando, H.; Ishida, H.; Kiso, M.; Ishihara, H.; Koketsu, M.
    Synthetic study on α(2→8)-linked oligosialic acid employing 1,5-lactamization as a key step
    Tetrahedron Lett. 2009, 50, 4478–4481. (2009/08/05)
  7. Magesh, S.; Savita, V.; Moriya, S.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
    Human sialidase inhibitors: Design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids
    Bioorg. Med. Chem. 2009, 17, 4595–4603. (2009/07/01)
  8. Ishibashi, Y.; Nagamatsu, Y.; Meyer, S.; Imamura, A.; Ishida, H.; Kiso, M.; Okino, N.; Geyer, R.; Ito, M.
    Transglycosylation-based fluorescent labeling of 6-gala series glycolipids by endogalactosylceramidase
    Glycobiology 2009, 19, 797–807. (2009/04/23)
  9. Iwayama, Y.; Ando, H.; Ishida, H.; Kiso, M.
    A First Total Synthesis of Ganglioside HLG-2
    Chem. Eur. J. 2009, 15, 4637–4648. (2009/04/17)
  10. Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Ganglioside GQ1b: Efficient Total Synthesis and the Expansion to Synthetic Derivatives To Elucidate Its Biological Roles
    J. Org. Chem. 2009, 74, 3009–3023. (2009/03/18)
  11. Kawasaki, N.; Lin, C. W.; Inoue, R.; Khoo, K. H.; Kawasaki, N.; Ma, B. Y.; Oka, S.; Ishiguro, M.; Sawada, T.; Ishida, H.; Hashimoto, T.; Kawasaki, T.
    Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116
    Glycobiology 2009, 19, 437–450. (2009/01/07)
  12. Yamaguchi, M.; Ishida, H.; Kiso, M.
    Efficient Synthesis of Three Types of Sialyl 6-O-Sulfo Lewis X: Probes for the Comprehensive Search for the Interaction between Carbohydrates and Other Biomoleclues
    Heterocycles 2009, 77, 333–349. (2008/08/21)
  13. Sato, T.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Di-tert-butylsilylene-directed α-selective synthesis of p-nitrophenyl T-antigen analogues
    Glycoconj. J. 2009, 26, 83–98. (2008/08/16)

2008年

  1. Ando, H.
    Development of Efficient and Stereoselective Glycosylation Reactions, Effected by a Functional Group Remote from the Anomeric Center of the Glycosyl Donor
    Trends Glycosci. Glycotechnol. 2008, 20, 141–158. (2008/11/20)
  2. Yamaguchi, M.; Ishida, H.; Kiso, M.
    Total synthesis of 6-O-sulfo-sialylparagloboside: a widely useful glycoprobe for biochemical research
    Carbohydr. Res. 2008, 343, 1849–1857. (2008/11/03)
  3. Fujikawa, K.; Imamura, A.; Ishida, H.; Kiso, M.
    Synthesis of a GM3 ganglioside analogue carrying a phytoceramide moiety by intramolecular glycosylation as a key step
    Carbohydr. Res. 2008, 343, 2729–2734. (2008/11/03)
  4. Abdu-Allah, H. H. M.; Tamanaka, T.; Yu, J.; Zhuoyuan, L.; Sadagopan, M.; Adachi, T.; Tsubata, T.; Kelm, S.; Ishida, H.; Kiso, M.
    Design, Synthesis, and Structure−Affinity Relationships of Novel Series of Sialosides as CD22-Specific Inhibitors
    J. Med. Chem. 2008, 51, 6665–6681. (2008/10/08)
  5. Stenmark, P.; Dupuy, J.; Imamura, A.; Kiso, M.; Stevens, R. C.
    Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction
    PLOS Pathog. 2008, 4, e1000129. (2008/08/15)
  6. Sawada, T.; Hashimoto, T.; Tokiwa, H.; Suzuki, T.; Nakano, H.; Ishida, H.; Kiso, M.; Suzuki, Y.
    Ab initio fragment molecular orbital studies of influenza virus hemagglutinin–sialosaccharide complexes toward chemical clarification about the virus host range determination
    Glycoconj. J. 2008, 25, 805–815. (2008/06/24)
  7. Ashida, H.; Maki, R.; Ozawa, H.; Tani, Y.; Kiyohara, M.; Fujita, M.; Imamura, A.; Ishida, H.; Kiso, M.; Yamamoto, K.
    Characterization of two different endo-α-N-acetylgalactosaminidases from probiotic and pathogenic enterobacteria, Bifidobacterium longum and Clostridium perfringens
    Glycobiology 2008, 18, 727–734. (2008/06/17)
  8. Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    DTBS Effect: The Unique Sterically Driven Director for α-Galactosylation
    Heterocycles 2008, 76, 883–908. (2008/05/29)
  9. Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    DTBS(di-tert-butylsilylene)-directed α-Galactosylation for the Synthesis of Biologically Relevant Glycans
    Curr. Org. Chem. 2008, 12, 675–689. (2008/05-06)
  10. Komori, T.; Ando, T.; Imamura, A. Li, Y. T.; Ishida, H.; Kiso, M.
    Design and efficient synthesis of novel GM2 analogues with respect to the elucidation of the function of GM2 activator
    Glycoconj. J. 2008, 25, 647–661. (2008/03/27)
  11. Yoshikawa, T.; Kato, Y.; Yuki, N.; Yabe, T.; Ishida, H.; Kiso, M.
    A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH
    Glycoconj. J. 2008, 25, 545–553. (2008/02/15)
  12. Imamura, A.; Yoshikawa, T.; Komori, T.; Ando, M.; Ando, H.; Wakao, M.; Suda, Y.; Ishida, H.; Kiso, M.
    Design and synthesis of versatile ganglioside probes for carbohydrate microarrays
    Glycoconj. J. 2008, 25, 269–278. (2008/01/16)
  13. Magesh, S.; Moriya, S.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
    Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: Selective inhibitors of lysosomal sialidase (NEU1)
    Bioorg. Med. Chem. Lett. 2008, 18, 532–537. (2008/01/15)
  14. Li, Y.-T.; Li, S.-C.; Kiso, M.; Ishida, H.; Mauri, L.; Raimondi, L.; Bernardi, A.; Sonnino, S.
    Effect of structural modifications of ganglioside GM2 on intra-molecular carbohydrate-to-carbohydrate interaction and enzymatic susceptibility
    Biochim. Biophys. Acta Gen. Subj. 2008, 1780, 353–361. (2007/10/05)

2007年

  1. Ando, H.
    The Unusual Is Interesting: New Aspect of Glycosyl Donor Is Reveled (GLYCOTOPIC)
    Trends Glycosci. Glycotechnol. 2007, 19, 271–272. (2007/11/02)
  2. Yu, J.; Sawada, T.; Adachi, T.; Gao, X.; Takematsu, H.; Kozutsumi, Y.; Ishida, H.; Kiso, M.; Tsubata, T.
    Synthetic glycan ligand excludes CD22 from antigen receptor-containing lipid rafts
    Biochem. Biophys. Res. Commun. 2007, 360, 759–764. (2007/07/05)
  3. Yoon, S.-J.; Ikeda, S.; Sadilek, M.; Hakomori, S.-i.; Ishida, H.; Kiso, M.
    Self-recognition of N-linked glycans with multivalent GlcNAc, determined as ceramide mimetic conjugate
    Glycobiology 2007, 17, 1007–1014. (2007/07/02)
  4. Takaku, H.; Ishida, H.-k.; Fujita, M.; Inazu, T.; Ishida, H.; Kiso, M.
    A Chemical Synthesis of GlcNAcβ(1→4)GlcUA-UDP to Elucidate the Catalytic Mechanism of Hyaluronic Acid Synthases (HAS)
    Synlett 2007, 818–820. (2007/03/08)
  5. Sawada, T.; Hashimoto, T.; Nakano, H.; Suzuki, T.; Suzuki, Y.; Kawaoka, Y.; Ishida, H.; Kiso, M.
    Influenza viral hemagglutinin complicated shape is advantageous to its binding affinity for sialosaccharide receptor
    Biochem. Biophys. Res. Commun. 2007, 355, 6–9. (2007/02/05)
  6. Ishibashi, Y.; Nakasone, T.; Kiyohara, M.; Horibata, Y.; Sakaguchi, K.; Hijikata, A.; Ichinose, S.; Omori, A.; Yasui, Y.; Imamura, A.; Ishida, H.; Kiso, M.; Okino, N.; Ito, M.
    A Novel Endoglycoceramidase Hydrolyzes Oligogalactosylceramides to Produce Galactooligosaccharides and Ceramides
    J. Biol. Chem. 2007, 282, 11386–11396. (2007/01/23)

2006年

  1. Yamada, S.; Suzuki, Y.; Suzuki, T.; Le, M. Q.; Nidom, C. A.; Sakai-Tagawa, Y.; Muramoto, Y.; Ito, M.;  Kiso, M.; Horimoto, T.; Shinya, K.; Sawada, T.; Kiso, M.; Usui, T.; Murata, T.; Lin, Y.; Hay, A.; Haire, L. F.; Stevens, D. J.; Russell, R. J.; Gamblin, S. J.; Skehel, J. J.; Kawaoka, Y.
    Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors
    Nature 2006, 444, 378–382. (2006/11/16)
  2. Imamura, A.; Kimura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Extended Applications of Di-tert-butylsilylene-Directed α-Predominant Galactosylation Compatible with C2-Participating Groups toward the Assembly of Various Glycosides
    Chem. Eur. J. 2006, 12, 8862–8870. (2006/11/16)
  3. Takaku, H.; Sato, J.; Ishida, H.-k.; Inazu, T.; Ishida, H.; Kiso, M.
    A chemical synthesis of UDP-LacNAc and its regioisomer for finding ‘oligosaccharide transferases’
    Glycoconj. J. 2006, 23, 565–573. (2006/11)
  4. Ando, H.
    Reaching the Summit of Mt. Oligosialic Acid (GLYCOTOPIC)
    Trends Glycosci. Glycotechnol. 2006, 18, 403–404. (2006/11/02)
  5. Sawada, T.; Hashimoto, T.; Nakano, H.; Suzuki, T.; Ishida, H.; Kiso, M.
    Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies
    Biochem. Biophys. Res. Commun. 2006, 351, 40–43. (2006/10/12)
  6. Kimura, A.; Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    A Novel Synthetic Route to α-Galactosyl Ceramides and iGb3 Using DTBS-Directed α-Selective Galactosylation
    Synlett 2006, 2379–2382. (2006/09/08)
  7. Makimura, Y.; Watanabe, S.; Suzuki, T.; Suzuki, Y.;Ishida, H.; Kiso, M.; Katayama, T.; Kumagai, H.; Yamamoto, K.
    Chemoenzymatic synthesis and application of a sialoglycopolymer with a chitosan backbone as a potent inhibitor of human influenza virus hemagglutination
    Carbohydr. Res. 2006, 341, 1803–1808. (2006/08/14)
  8. Attrill, H.; Imamura, A.; Sharma, R. S.; Kiso, M.; Crocker, P. R.; Van Aalten, D. M.
    Siglec-7 Undergoes a Major Conformational Change When Complexed with the α(2,8)-Disialylganglioside GT1b
    J. Biol. Chem. 2006, 281, 32774–32783. (2006/08/08)
  9. Ando, H.; Shimizu, H.; Katano, Y.; Koike, Y.; Koizumi, S.; Ishida, H.; Kiso, M.
    Studies on the α-(1→4)- and α-(1→8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides
    Carbohydr. Res. 2006, 341, 1522–1532. (2006/07/24)
  10. Fuse, T.; Ando, H.; Imamura, A.; Sawada, N.; Ishida, H.; Kiso, M.; Ando, T.; Li, S. C.; Li, Y. T.
    Synthesis and enzymatic susceptibility of a series of novel GM2 analogs
    Glycoconj. J. 2006, 23, 329–343. (2006/07)
  11. Ando, H.; Ishida, H.; Kiso, M.
    Study on the Method for Oligosaccharide Synthesis Covering the Structural Diversity of Sialic Acid
    J. Synth. Org. Chem. Jpn. 2006, 64, 481–491. (2006/05/01)
  12. Attrill, H.; Takazawa, H.; Witt, S.; Kelm, S.; Isecke, R.; Brossmer, R.; Ando, T.; Ishida, H.;
    Kiso, M.;  Crocker, P. R.; van Aalten, D. M. F.
    The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
    Biochem. J. 2006, 397, 271–278. (2006/04/20)
  13. Sawada, T.; Hashimoto, T.; Nakano, H.; Shigematsu, M.; Ishida, H.; Kiso, M.
    Conformational Study of α-N-Acetyl-d-Neuraminic Acid by Density Functional Theory
    J. Carbohydr. Chem. 2006, 25, 387–405. (Accepted: 2006/04/16)
  14. Sadagopan, M.; Suzuki, T.; Miyagi, T.; Ishida, H.; Kiso, M.
    Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2: Hints for the design of selective NEU3 inhibitors
    J. Mol. Graph. Model. 2006, 25, 196–207. (2006/01/19)
  15. Ohmori, K.; Fukui, F.; Kiso, M.; Imai, T.; Yoshie, O.; Hasegawa, H.; Matsushima, K.; Kannagi, R.
    Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells
    Blood 2006, 107, 3197–3204. (Accepted: 2005/11/28)

2005年

  1. Ando, H.; Koike, Y.; Koizumi, S.; Ishida, H.; Kiso, M.
    1,5-Lactamized Sialyl Acceptors for Various Disialoside Syntheses: Novel Method for the Synthesis of Glycan Portions of Hp-s6 and HLG-2 Gangliosides
    Angew. Chem. Int. Ed. 2005, 44, 6759–6763. (2005/10/14)
  2. Imamura, A.; Ando, H.; Ishida, H.; Kiso, M.
    Di-tert-butylsilylene-Directed α-Selective Synthesis of 4-Methylumbelliferyl T-Antigen
    Org. Lett. 2005, 7, 4415–4418. (2005/09/01)
  3. Shinya, K.; Hatta, M.; Yamada, S.; Takada, A.; Watanabe, S.; Halfmann, P.; Horimoto, T.; Neumann, G.; Kim, J. H.; Lim, W.; Guan, Y.; Peiris, M.; Kiso, M.; Suzuki, T.; Suzuki, Y.; Kawaoka, Y.
    Characterization of a Human H5N1 Influenza A Virus Isolated in 2003
    J. Virol. 2005, 79, 9926–9932. (2005/07/13)
  4. Otsubo, N.; Ishida, H.; Kannagi, R.; Kiso, M.
    Design and synthesis of a novel neo-glycolipid containing sialyl Lewis X determinant carried on the mucin GlcNAcβ1-6GalNAcα core structure
    Tetrahedron: Asymmetry 2005, 16, 1321–1327. (2005/04/04)
  5. Yamaguchi, M.; Ishida, H.; Kanamori, A.; Kannagi, R.; Kiso, M.
    6-O-Sulfo sialylparagloboside and sialyl Lewis X neo-glycolipids containing lactamized neuraminic acid: Synthesis and antigenic reactivity against G159 monoclonal antibody
    Glycoconj. J. 2005, 22, 95–108. (2005/03)

2004年

  1. Ando, H.; Imamura, A.
    Proceedings in Synthetic Chemistry of Sialo-Glycoside
    Trends Glycosci. Glycotechnol. 2004, 16, 293–303. (2004/09/02)
  2. Miyazaki, K.; Ohmori, K.; Izawa, M.; Koike, T.; Kumamoto, K.; Furukawa, K.; Ando, T.; Kiso, M.; Yamaji, T.; Hashimoto, Y.; Suzuki, A.; Yoshida, A.; Takeuchi, M.; Kannagi, R.
    Loss of Disialyl Lewisa, the Ligand for Lymphocyte Inhibitory Receptor Sialic Acid-Binding Immunoglobulin-Like Lectin-7 (Siglec-7) Associated with Increased Sialyl Lewisa Expression on Human Colon Cancers
    Cancer Res. 2004, 64, 4498–4505. (2004/07)
  3. Yamaguchi, M.; Ishida, H.; Kanamori, A.; Kannagi, R.; Kiso, M.
    Synthesis and Antigenic Property of a Novel Sialyl 6-O-Sulfo Lewis X Neo-glycolipid Containing Lactamized Neuraminic Acid
    J. Carbohydr. Chem. 2004, 23, 201–215. (Accepted: 2004/03/22)
  4. Matsuura, K.; Oda R.; Kitakouji, H.; Kiso, M.; Kitajima, K.; Kobayashi, K.
    Surface Plasmon Resonance Study of Carbohydrate−Carbohydrate Interaction between Various Gangliosides and Gg3-Carrying Polystyrene
    Biomacromolecules 2004, 5, 937–941. (2004/03/18)

2003年

  1. Li, Y.-T.; Li, S.-C.; Ishida, H.; Kiso, M.; Raimondi, L.; Bernardi, A.; Sonnino, S.
    Structural Basis for the Enzymatic Resistance of the GM2 Ganglioside
    Methods Enzymol. 2003, 363, 242–264. (2004/01/07)
  2. Yamaguchi, M.; Ishida, H.; Kanamori, A.; Kannagi, R.; Kiso, M.
    Studies on the endogenous L-selectin ligands: systematic and highly efficient total synthetic routes to lactamized-sialyl 6-O-sulfo Lewis X and other novel gangliosides containing lactamized neuraminic acid
    Carbohydr. Res. 2003, 338, 2793–2812. (2003/11/21)
  3. Hara-Yokoyama, M.; Ito, H.; Ueno-Noto, K.; Takano, K.; Ishida, H.; Kiso, M.
    Novel sulfated gangliosides, high-affinity ligands for neural siglecs, inhibit NADase activity of leukocyte cell surface antigen CD38
    Bioorg. Med. Chem. Lett. 2003, 13, 3441–3445. (2003/10/20)
  4. Hori, K.; Sawada, N.; Ando, H.; Ishida, H.; Kiso, M.
    Synthetic Study on Campylobacter jejuni Lipopolysaccharides: An Improved Synthesis of a Branched, Heptose-Containing Trisaccharide Core Structure and Its Conversion into Ganglioside GD3 Related Hexasaccharide
    Eur. J. Org. Chem. 2003, 3752–3760. (2003/09/16)
  5. Ando, H.; Koike, Y.; Ishida, H.; Kiso, M.
    Extending the possibility of an N-Troc-protected sialic acid donor toward variant sialo-glycoside synthesis
    Tetrahedron Lett. 2003, 44, 6883–6886. (2003/09/01)
  6. Fukunaga, K.; Toyoda, T.; Ishida, H.; Kiso, M.
    Synthesis of Lacto- and Neolacto-series Ganglioside Analogs Containing N-Glycolylneuraminic Acid: Probes for Investigation of Specific Receptor Structures Recognized by Influenza A Viruses
    J. Carbohydr. Chem. 2003, 22, 919–937. (Accepted: 2003/08/26)
  7. Imamura, A.; Ando, H.; Korogi, S.; Tanabe, G.; Muraoka, O.; Ishida, H.; Kiso, M.
    Di-tert-butylsilylene (DTBS) group-directed α-selective galactosylation unaffected by C-2 participating functionalities
    Tetrahedron Lett. 2003, 44, 6725–6728. (2003/08/25)
  8. Tamai, R.; Asai, Y.; Hashimoto, M.; Fukase, K.; Kusumoto, S.; Ishida, H.; Kiso, M.; Ogawa, T.
    Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4
    Immunology 2003, 110, 66–72. (2003/08/22)
  9. Ito, H.; Ishida, H.; Collins, B. E.; Fromholt, S. E.; Schnaar, R. L.; Kiso, M.
    Systematic synthesis and MAG-binding activity of novel sulfated GM1b analogues as mimics of Chol-1 (α-series) gangliosides: highly active ligands for neural siglecs
    Carbohydr. Res. 2003, 338 , 1621–1639. (2003/07/29)
  10. Ishihara, A.; Ishida, H.; Ikami, T.; Tomiya, N.; Ando, H.; Kiso, M.
    Synthesis and Selectin-Blocking Activity of a Novel Analog of Sulfatide: 3-C-Carboxymethylgalactosyl Lipid
    J. Carbohydr. Chem. 2003, 22, 513–520. (Accepted: 2003/07/02)
  11. Tsuchida, A.; Okajima, T.; Furukawa, K.; Ando, T.; Ishida, H.; Yoshida, A.; Nakamura, Y.; Kannagi, R.; Kiso, M.; Furukawa, K.
    Synthesis of Disialyl Lewis a (Lea) Structure in Colon Cancer Cell Lines by a Sialyltransferase, ST6GalNAc VI, Responsible for the Synthesis of α-Series Gangliosides
    J. Biol. Chem. 2003, 278, 22787–22794. (2003/03/31)
  12. Ando, T.; Ishida, H.; Kiso, M.
    First total synthesis of α-(2→3)/α-(2→6)-disialyl lactotetraosyl ceramide and disialyl Lewis A ganglioside as cancer-associated carbohydrate antigens
    Carbohydr. Res. 2003, 338, 503–514. (2003/03/14)
  13. Hamada, T.; Hirota, H.; Yokoyama, S.; Yamaguchi, M.; Otsubo, N.; Ishida, H.; Kiso, M.; Kanamori, A.; Kannagi, R.
    NMR structure elucidation of cyclic sialyl 6-sulfo Lewis x, a biologically dormant form of L-selectin ligand
    Tetrahedron Lett. 2003, 44, 1167–1170. (2003/02/03)