Curriculum Vitae
Professor Toshiaki Murai was born in Osaka, Japan on December 23, 1957. He received a B.S. degree in petroleum chemistry in 1980 from Osaka University. He joined Professor Shinzi Kato's group at Gifu University as a research assistant in 1983. He obtained a Ph.D. in organic chemistry from Osaka University in 1986 under the guidance of Professor Shinji Murai (supervisor: Professor Noboru Sonoda). He worked as a postdoctoral fellow in Professor Sessler's group at the University of Texas at Austin for two years from 1986. In June 1990, he was promoted to Associate Professor and in April 2001 was promoted to Full Professor.
e-mail: mtoshi:gifu-u.ac.jp (please change : to @)
Phone:+81-58-293-2614 FAX: +81-58-230-1893
Recent Selected Publications:
• Synthesis and Properties of 1-Methylthiopropargylammonium Salts and Their Use as Key Precursors to Sulfur-Containing Enediynes, Murai, T.; Fukushima, K.; Mutoh, Y. Org. Lett. 2007, 9(25), 5295-5298.
• Sequential Addition Reactions of Lithium Acetylides and Grignard Reagents to Selenoiminium Salts Leading to 2-Propynyl Tertiary Amines Bearing a Tetrasubstituted Carbon Center, Murai, T.; Nogawa, S. Mutoh, Y. Bull. Chem. Soc. Jpn. 2007, 80(11) 2220-2225.
• Synthesis of 1,1f-Binaphthyl-2,2f-diyl Phosphoroselenoic Ammonium Salts and Their Conversion to Optically Active Dialkyl Diselenides, Murai, T.; Monzaki, M.; Shibahara, F. Chem. Lett. 2007, 36(7), 852-853.
• Three-Component Coupling Reactions of Thioformamides with Organolithium and Grignard Reagents Leading to Formation of Tertiary Amines and a Thiolating Agent, Murai, T.; Asai, F. J. Am. Chem. Soc. 2007, 129(4), 780-781.
• Telluration of Seleno- and Chloroiminium Salts Leading to Various Telluroamides, and Their Structure and NMR Properties, Mutoh, Y.; Murai, T.; Yamago, S. J. Organomet. Chem. 2007, 692, 129-135.
• gScience of Synthesish Selenium- and Tellurium-Containing Acetals, Murai, T.; Yoshimatsu, M., Thieme, 2007, 30, 597-637.
• Synthesis of 1,1f-Binaphthyl-2,2f-diyl Phosphoroselenoic Amides and Their Conversion to Optically Pure Phosphoramidites, Murai, T.;. Inaji, S.; Morishita, K.; Shibahara, F.; Tokunaga, M.; Obora, Y.; Tsuji, Y. Chem. Lett. 2006, 35(12), 1424-1425.
• Sequential Addition Reaction of Lithium Acetylides and Grignard Reagents to Thioiminium Salts from Thiolactams Leading to 2,2-Disubstituted Cyclic Amines, T. Murai, R. Toshio, and Y. Mutoh, Tetrahedron 62(26), 6312-6320 (2006).
• 1,1'-Binaphthyl-2,2'-diyl Phosphoroselenoyl Chloride as a Chiral Molecular Tool for the Preparation of Enantiomerically Pure Alcohols and Amines, T. Murai, D. Matsuoka, and K. Morishita, J. Am. Chem. Soc. 128(14), 4584-4585 (2006).
• Substituent effects on [1,3]-rearrangement of alkynyl S,N-acetals to 1-amino-3-sulfenylallenes and their conversion to a,b-unsaturated ketones, T. Murai, Y. Mutoh, and K. Fukushima, Lett. Org. Chem. 3, 409-413 (2006).
• "Science of Synthesis", Bis(organochalcogeno)acetylenes, 1-Nitrogen-Functionalized-2-(Organochalcogeno)acetylenes, 2-Phosphorus-Functionalized-1-(Organochalcogeno)acetylenes, T. Murai, Thieme, 24, 849-864 (2006).
• "Comprehensive Organic Functional Group Transformation II", Functions with Two Chalcogens Other than Oxygen, T. Murai, Elsevier, 5, 493-518 (2005).
• "Topics in Current Chemistry", Thio-, Seleno-, Telluro-amides, T. Murai, Springer-Verlag, 251, 247-272 (2005).
• "Science of Synthesis", Tellurocarboxylic Acids and Derivatives, T. Murai, Thieme, 22, 213-219 (2005).
• Optically Active P-Chiral Phosphinoselenoic Amides: Stereochemical Outcome at the P-Chirogenic Center in the Synthesis of These Substances and Their Characterization, T. Kimura and T. Murai, Tetrahedron Asymmetry 16(22), 3703-3710 (2005).
• N-Thioacyl 1,3-Amino Alcohols: Synthesis via Ring-Opening of Oxiranes with Thioamide Dianions and Applications as Key Intermediates Leading to Stereochemically Defined 5,6-Dihydro-4H-1,3-oxazines and 1,3-Amino Alcohols, T. Murai, H. Sano, H. Kawai, H. Aso, and F. Shibahara, J. Org. Chem. 70(20), 8148-8153 (2005).
• Enantiomerically Pure P-Chiral Phosphinoselenoic Chlorides: Inversion of Configuration at the P-Chirogenic Center in the Synthesis and Reaction of These Substances, T. Kimura and T. Murai, Chem. Commun. (2005) (32), 4077-4078.
• Phosphinoselenothioic Acids and Their Salts: Synthesis, Characterization and Reaction with Electrophiles, T. Kimura, T. Murai, A. Miwa, D. Kurachi, H. Yoshikawa, and S. Kato, J. Org. Chem. 70(14), 5611-5617 (2005).
• Addition Reaction of Zinc Acetylides to Thioiminium Salts Leading to 3-Amino-1-sulfenyl-1,4-enynes, T. Murai, Y. Ohta, and Y. Mutoh, Tetrahedron Lett. 46(21), 3637-3640 (2005).
• Selenophilic Reaction of Organolithium and Magnesium Reagents with Phosphinoselenoic Chlorides, T. Kimura, T. Murai, and N. Mizuhata, Heteroat. Chem. 16(3) 185-191 (2005).
• P-Chiral Phosphinoselenoic Chlorides and Phosphinochalcogenoselenoic Acid Esters: Synthesis, Characterization and Conformational Studies, T. Kimura and T. Murai, J. Org. Chem. 70(3), 952-959 (2005).
• Syntheses and Reactions of Selenothioic acid S-Esters and Diselenoic Acid Esters, T. Murai, Synlett 1509-1520 (2005).
• Acyclic Telluroiminium Salts: Isolation and Characterization, Y. Mutoh, T. Murai, and S. Yamago, J. Am. Chem. Soc. 126(51), 16696-16697 (2004).
• Synthesis and Properties of Selenoiminium Salts Derived from Secondary Selenoamides, Y. Mutoh and T. Murai, Organometallics 23(16), 3907-3913 (2004).
• Generation and Reactions of Selenium Isologues of Enolate Ions, T. Murai, Mini Rev. in Org. Chem. 1(3) 279-290 (2004).
• P-Chiral Phosphinoselenoic Chlorides and Optically Active P-Chiral Phosphinoselenoic Amides: Synthesis and Stereospecific Interconversion with Extrusion and Addition Reactions of the Selenium Atom,T. Kimura and T. Murai, Chem. Lett. 33(7), 878-879 (2004).
• Synthesis of Tertiary Propargylamines by Sequential Reactions of in Situ Generated Thioiminium Salts with Organolithium and -magnesium Reagents, T. Murai, Y. Mutoh, Y. Ohta, and M. Murakami, J. Am. Chem. Soc. 126(19), 5968-5969 (2004).
• Reaction of an Ammonium Eneselenolate Derived from a Selenothioacetic Acid S-Ester with Electron-Deficient Alkenes and Alkynes, T. Murai, T. Kondo, S. Kato, Heteroat. Chem. 15(2), 187-192(2004).
• Iodo-cyclization of N-Homoallyl Thioamides Leading to 5,6-Dihydro-2,4-diaryl-4H-1,3-thiazines, T. Murai, H. Niwa, T. Kimura, F. Shibahara, Chem. Lett., 33(5), 508-509 (2004).
• Reaction and characterization of thioamide dianions derived from N-benzyl thioamides, T. Murai, H. Aso, Y. Tatematsu, Y. Itoh, H. Niwa, S. Kato, J. Org. Chem. 68, 8514-8519(2003).
• Highly efficient peterson olefination leading to unsaturated selenoamides and their characterization, T. Murai, A. Fujishima, C. Iwamoto, S. Kato, J. Org. Chem. 68(21), 7979-7982(2003).
• Acyclic selenoiminium salts: isolation, first structural characterization, and reactions, Y. Mutoh, T. Murai, Org. Lett. 5(8), 1361-1364 (2003).
• Reaction of lithium eneselenolates derived from selenoamides with ketones: a highly diastereoselective synthetic route to a-disubstituted a-hydroxy selenoamides, T. Murai, M. Ishizuka, A. Suzuki, S. Kato, Tetrahedron Lett. 44, 1343-1346 (2003).
• Selenothiophosphinic acid salts: efficient synthesis, structure, and reactivity, T. Murai, T. Kimura, A. Miwa, D. Kurachi and S. Kato, Chem. Lett. (9), 914-915 (2002).
• The first ammonium aromatic diselenoates: stable heavy congeners of aromatic carboxylic acid salts, K. Tani, T. Murai and S. Kato, J. Am. Chem. Soc. 124, 5960-5961 (2002).
• Synthesis and structure of group 14 element derivatives of carbotelluroates, K. Tani, R. Yamada, T. Kanda, M. Suzuki, S. Kato and T. Murai, Organometallics 21, 1487-1492 (2002).
• Generation and reactions of a selenoamide dianion, T. Murai, H. Aso and S. Kato, Org. Lett. 4, 1407-1409 (2002).
• Ammonium eneselenolates: stereochemistry and electronic properties, T. Murai, S. Hayakawa and S. Kato, J. Org. Chem. 66, 8101-8105 (2001).
• Ammonium eneselenolates: stereochemical and spectroscopic properties, T. Murai, S. Hayakawa, Y. Miyazaki and S. Kato, Phosphorus Sulphur and Silicon 172, 111-118 (2001).
• Reactions of lithium eneselenolates of selenoamides with carbonyl compounds, T. Murai, A. Suzuki, M. Takagi and S. Kato, Phosphorus Sulphur and Silicon 172, 101-109 (2001).
• The first alkali metal selenothioates: synthesis and molecular structure, O. Niyomura, K. Sakai, T. Murai, S. Kato and S. Yamaguchi, K. Tamao, Chem. Lett. (10). 968-969 (2001).
• Aldol-type condensation reaction of lithium eneselenolates generated from selenoamides with aldehdyes, T. Murai, A. Suzuki and S. Kato, J. Chem. Soc. Perkin 1 (2001) 2711-2716.
• MeOTf-mediated alkynylation of selenoamides leading to a-methylselenenyl a,b-unsaturated ketones and their characterization, T. Murai, Y. Mutoh and S. Kato, Org. Lett. 3(13), 1993-1995 (2001).