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Near-infrared fluorescent HaloTag ligands for efficient organelle labelling in live cells
Y. Tanaka, M.Taki, S. Yamaguchi
Chem. Commun., 61, 1164-1167 (2025).
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Dicopper Complexes of p-Cresol-2,6-bis(amide-tether-dpa4-X) (X = MeO and Cl): Selective ROS Generation and Cytotoxicity Enhancement Controlled by Electronic and Hydrophobic Effects of the MeO and Cl Groups
M. Hata, Y. Kadoya, J. Ueno, M. Taki, M. Kodera
Inorg. Chem., 63, 13893–13902 (2024).
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Fluorescence Lifetime Imaging of Lipid Heterogeneity in the InnerMitochondrial Membrane with a Super-photostable Environment-Sensitive Probe
J. Wang, M. Taki, Y. Ohba, M. Arita, S. Yamaguchi
Angew. Chem. Int. Ed., 63, e202404328 (2024).
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Stereochemistry-Dependent Labeling of Organelles with a Near-Infrared-Emissive Phosphorus-Bridged Rhodamine Dye in Live-Cell Imaging
Q. Wu, M. Taki, Y. Tanaka, M. Kesherwani, Q. M. Phung, S. Enoki, Y. Okada, F. Tama, S. Yamaguchi
Angew. Chem. Int. Ed., 63, e202400711 (2024).
Selected as a Very Important Paper
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Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an Activatable Covalent Fluorescent Probe Compatible with Tissue Clearing
D. M. Sakamoto, I. Tamura, B. Yi, S. Hasegawa, Y. Saito, N. Yamada, Y. Takakusagi, S. I. Kubota, M. Kobayashi, H. Harada, K. Hanaoka, M. Taki, M. Nangaku, K. Tainaka, S. Sando
ACS Nano, 18, 5167–5179 (2024).
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Secretion of Mitochondrial DNA via Exosomes Promotes Inflammation in Behçet’s Syndrome
H. Konaka, Y. Kato, T. Hirano, K. Tsujimoto, J. Park, T. Koba, W. Aoki, Y. Matsuzaki, M. Taki, S. Koyama, E. Itotagawa, T. Jo, T. Hirayama, T. Kawai, K. J Ishii, M. Ueda, S. Yamaguchi, S. Akira, T. Morita, Y. Maeda, M. Nishide, S. Nishida, Y. Shima, M. Narazaki, H. Takamatsu, A. Kumanogoh
EMBO J., 42, e112573 (2023).
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A Synthetic Strategy for Multi-Functionalized Phospharhodamines via Catalytic P-Arylation
Y. Asada, M. Taki, S. Yamaguchi
Bull. Chem. Soc. Jpn., 96, 601–606 (2023).
Selected as a Very Important Paper
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A negative-solvatochromic fluorescent probe for visualizing intracellular distributions of fatty acid metabolites
K. Kajiwara, H. Osaki, S. Greßies, K. Kuwata, J. H. Kim, T. Gensch, Y. Sato, F. Glorius, S. Yamaguchi, M. Taki
Nat. Commun., 13, 2533 (2022).
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Pro-tumoral behavior of omental adipocyte-derived fibroblasts in tumor microenvironment at the metastatic site of ovarian cancer
S. Iyoshi, M. Yoshihara, K. Nakamura, M. Sugiyama, Y. Koya, K. Kitami, K. Uno, K. Mogi, S. Tano, H. Tomita, K. Kajiwara, M. Taki, S. Yamaguchi, A. Nawa, H. Kajiyama
Int. J. Cancer, 149, 1961–1972 (2021).
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Late-stage functionalisation of alkyne-modified phospha-xanthene dyes: lysosomal imaging using an off-on-off type of pH probe
H. Ogasawara, Y. Tanaka, M. Taki, S. Yamaguchi
Chem. Sci., 22, 7902–7907 (2021).
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Donor-acceptor-acceptor-type near-infrared fluorophores that contain dithienophosphole oxide and boryl groups: Effect of the boryl group on the nonradiative decay
Y. Sugihara, N. Inai, M. Taki, T. Baumgartner, R. Kawakami, T. Saitou, T. Imamura, T. Yanai, S. Yamaguchi
Chem. Sci., 22, 6333–6341 (2021).
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Fused Thiophene- S, S-dioxide-Based Super-Photostable Fluorescent Marker for Lipid Droplets
M. Taki, K. Kajiwara, E. Yamaguchi, Y. Sato, S. Yamaguchi
ACS Mater. Lett., 3, 42–49 (2021).
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Covalent Self-labeling of tagged proteins with chemical fluorescent dyes in BY-2 cells and arabidopsis seedlings
R. J. Iwatate, A. Yoshinari, N. Yagi, M. Grzybowski, H. Ogasawara, M. Kamiy, T. Komatsu, M. Taki, S. Yamaguchi, W. B. Frommer, M. Nakamura
Plant Cell, 32, 3081–3094 (2020).
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Phosphole-Oxide-Based Fluorescent Probe for Super-resolution Stimulated Emission Depletion Live Imaging of the Lysosome Membrane
C. Wang, M. Taki, K. Kajiwara, J. Wang, S. Yamaguchi
ACS Mater. Lett., 2, 705–711 (2020).
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Effects of Amino Group Substitution on the Photophysical Properties and Stability of Near-Infrared Fluorescent P-Rhodamines
M. Grzybowski, M. Taki, K. Kajiwara, S. Yamaguchi
Chem. Eur. J., 26, 7912–7917 (2020).
Selected as Hot Paper
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The Effect of Branching on the One- and Two-Photon Absorption, Cell Viability, and Localization of Cationic Triarylborane Chromophores with Dipolar versus Octupolar Charge Distributions for Cellular Imaging
S. Griesbeck, E. Michail, F. Rauch, H. Ogasawara, C. Wang, Y. Sato, R.M. Edkins, Z. Zhang, M. Taki, C. Lambert, S. Yamaguchi, T. B. Marder
Chem. Eur. J., 25, 13164–13175 (2019).
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A photostable fluorescent marker for the superresolution live imaging of the dynamic structure of the mitochondrial cristae
C. Wang, M. Taki, Y. Sato, Y. Tamura, H. Yaginuma, Y. Okada, S. Yamaguchi
Proc. Natl. Acad. Sci. USA, 116, 15817–15822 (2019).
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Optimization of Aqueous Stability versus π-Conjugation in Tetracationic Bis(triarylborane) Chromophores: Applications in Live-Cell Fluorescence Imaging
S. Griesbeck, M. Ferger, C. Czernetzi, C. Wang, R. Bertermann, A. Friedrich, M. Haehnel, D. Sieh, M. Taki, S. Yamaguchi, T.B. Marder
Chem. Eur. J., 25, 7679–7688 (2019).
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Tuning the π-bridge of quadrupolar triarylborane chromophores for one- and two-photon excited fluorescence imaging of lysosomes in live cells
S. Griesbeck, E. Michail, C. Wang, H. Ogasawara, S. Lorenzen, L. Gerstner, T. Zang, J. Nitsch, Y. Sato, R. Bertermann, M. Taki, C. Lambert, S. Yamaguchi, T. B. Marder
Chem. Sci., 10, 5405–5422 (2019).
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A Highly Photostable Near-Infrared Labeling Agent Based on a Phospha-rhodamine for Long-Term and Deep Imaging
M. Grzybowski, M. Taki, K. Senda, Y. Sato, T. Ariyoshi, Y. Okada, R. Kawakami, T. Imamura, S. Yamaguchi
Angew. Chem. Int. Ed., 57, 10137–10141 (2018).
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A far-red fluorescent probe based on a phospha-fluorescein scaffold for cytosolic calcium imaging
H. Ogasawara, M. Grzybowski, R. Hosokawa, Y. Sato, M. Taki, S. Yamaguchi
Chem. Commun., 54, 299–302 (2018).
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Selective Conversion of P=O-Bridged Rhodamines into P=O-Rhodols: Solvatochromic Near-Infrared Fluorophores
M. Grzybowski, M. Taki, S. Yamaguchi
Chem. Eur. J., 23, 13028–13032 (2017).
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Super-Photostable Phosphole-Based Dye for Multiple-Acquisition Stimulated Emission Depletion Imaging
C. Wang, M. Taki, Y. Sato, A. Fukazawa, T. Higashiyama, S. Yamaguchi
J. Am. Chem. Soc., 139, 10374–10381 (2017).
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Water-Soluble N-Heterocyclic Carbene-Protected Gold Nanoparticles: Size-Controlled Synthesis, Stability, and Optical Properties
K. Salorinne, R. W. Y. Man, C.-H. Li, M. Taki, M. Nambo, C. M. Crudden
Angew. Chem. Int. Ed., 56, 6198–6202 (2017).
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Color-tunable fluorescent nanoparticles encapsulating trialkylsilyl-substituted pyrene liquids
M. Taki, S. Azeyanagi, K. Hayashi, S. Yamaguchi
J. Mater. Chem. C, 5, 2142–2148 (2017).
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A Macrocyclic Fluorophore Dimer with Flexible Linkers: Bright Excimer Emission with a Long Fluorescence Lifetime
H. Osaki, C.-M. Chou, M. Taki, K. Welke, D. Yokogawa, S. Irle, Y. Sato, T. Higashiyama, S. Saito, A. Fukazawa, S. Yamaguchi
Angew. Chem. Int. Ed., 55, 7131–7135 (2016).
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Phospha-fluorescein: A red-emissive fluorescein analogue with high photobleaching resistance
A. Fukazawa, S. Suda, M. Taki, E. Yamaguchi, M. Grzybowski, Y. Sato, T. Higashiyama, S. Yamaguchi
Chem. Commun., 52, 1120–1123 (2016).
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A Phosphole Oxide Based Fluorescent Dye with Exceptional Resistance to Photobleaching: A Practical Tool for Continuous Imaging in STED Microscopy
C. Wang, A. Fukazawa, M. Taki, Y. Sato, T. Higashiyama, S. Yamaguchi
Angew. Chem. Int. Ed., 54, 15213–15217 (2015).
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A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions
M. Taki, H. Ogasawara, H. Osaki, A. Fukazawa, Y. Sato, K. Ogasawara, T. Higashiyama, S. Yamaguchi
Chem. Commun., 51, 11880–11883 (2015).
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Environment-Sensitive Fluorescent Probe: A Benzophosphole Oxide with an Electron-Donating Substituent
E. Yamaguchi, C. Wang, A. Fukazawa, M. Taki, Y. Sato, T. Sasaki, M. Ueda, N. Sasaki, T. Higashiyama, S. Yamaguchi
Angew. Chem. Int. Ed., 54, 4539–4543 (2015).
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(32) Asymmetrical Distribution of Choline Phospholipids Revealed by Click Chemistry and Freeze-Fracture Electron Microscopy
S. Iyoshi, J. Cheng, T. Tatematsu, S. Takatori, M. Taki, Y. Yamamoto, A. Salic, T. Fujimoto
ACS Chem. Biol., 9, 2217–2222 (2014).
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A mitochondria-targeted turn-on fluorescent probe based on a rhodol platform for the detection of copper(I)
M. Taki, K. Akaoka, K. Mitsui, Y. Yamamoto
Org. Biomol. Chem., 12, 4999–5005 (2014).
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Rosamine-Based Fluorescent Sensor with Femtomolar Affinity for the Reversible Detection of a Mercury Ion
M. Taki, K. Akaoka, S. Iyoshi, Y. Yamamoto
Inorg. Chem., 51, 13075–13077 (2012).
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Development of a Dual Functional Luminescent Sensor for Zinc Ion Based on a Peptidic Architecture
T. Hirayama, M. Taki, K. Akaoka, Y. Yamamoto
Bioorg. Med. Chem. Lett., 22, 7410–7413 (2012).
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Structural Insights into the Substrate Specificity of Bacterial Copper Amine Oxidase Obtained by Using Irreversible Inhibitors
T. Murakawa, H. Hayashi, M. Taki, Y. Yamamoto, Y. Kawano, K. Tanizawa, T. Okajima
J. Biochem., 151, 167–178 (2012).
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Development of a Cholesterol-Conjugated Fluorescent Sensor for Site-Specific Detection of Zinc Ion at the Plasma Membrane
S. Iyoshi, M. Taki, Y. Yamamoto
Org. Lett., 13, 4558–4561 (2011).
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Electron microscopic visualization of the filament binding mode of actin-binding proteins
T. Ito, T. Hirayama, M. Taki, S. Iyoshi, S. Dai, S. Takeda, C. Kimura-Sakiyama, T. Oda, Y. Yamamoto, Y. Maéda, A. Narita
J. Mol. Biol., 408, 26-39 (2011).
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Human spire interacts with the barbed end of the actin filament
T. Ito, A. Narita, T. Hirayama, M. Taki, S. Iyoshi, Y. Yamamoto, Y. Maéda, T. Oda
J. Mol. Biol., 408, 18-25 (2011).
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Design and Synthesis of Fluorescent Probe for Polyhistidine Tag Using Macrocyclic Nickel(II) Complex and Fluorescein Conjugate
M. Taki, F. Asahi, T. Hirayama, Y. Yamamoto
Bull. Chem. Soc. Jpn., 84, 386-394 (2011).
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Development of Highly Sensitive Fluorescent Probes for Detection of Intracellular Copper(I) in Living Systems
M. Taki, S. Iyoshi, A. Ojida, I. Hamachi, Y. Yamamoto
J. Am. Chem. Soc., 132, 5938–5939 (2010).
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Development of ratiometric fluorescent probe for zinc ion based on indole fluorophore
M. Taki, Y. Watanabe, Y. Yamamoto
Tetrahedron Letters, 50, 1345–1347 (2009).
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Selective labeling of tag-fused protein by tryptophan-sensitized luminescence of a terbium complex
T. Hirayama, M. Taki, A. Kodan, H. Kato, Y. Yamamoto
Chemical Communications, , 3196–3198 (2009).
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Effects of heteroatom substitution on the structures, physicochemical properties, and redox behavior of nickel(II) complexes with pyridine-containing macrocyclic ligands
M. Taki, Y. Kawashima, N. Sakai, T. Hirayama, Y. Yamamoto
Bull. Chem. Soc. Jpn., 81, 590–597 (2008).
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Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor
M. Taki, M. Desaki, A. Ojida, S. Iyoshi, T. Hirayama, I. Hamachi, Y. Yamamoto
J. Am. Chem. Soc., 130, 12564–12565 (2008).
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Colorimetric response to mercury-induced abstraction of triethylene glycol ligands from a gold nanoparticle surface
T. Hirayama, M. Taki, Y. Kashiwagi, M. Nakamoto, A. Kunishita, S. Itoh, Y. Yamamoto
Dalton Trans., , 4705–4707 (2008).
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Further insight into the mechanism of stereoselective proton abstraction by bacterial copper amine oxidase
M. Taki, T. Murakawa, T. Nakamoto, M. Uchida, H. Hayashi, K. Tanizawa, Y. Yamamoto, T. Okajima
Biochemistry, 47, 7726–7733 (2008).
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Rosamine-based fluorescent chemosensor for selective detection of silver(I) in an aqueous solution
S. Iyoshi, M. Taki, Y. Yamamoto
Inorg. Chem., 47, 3946–3948 (2008).
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Synthesis of a new bifunctionalised fluorescent label and physical properties of the bound form on model peptide of troponin C
T. Hirayama, S. Iyoshi, M. Taki, Y. Maeda, Y. Yamamoto
Org. Biomol. Chem., 5, 2040-2045 (2007).
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Synthesis of a new water soluble 2,2-bifunctionalized spin label and its application to troponin C
T. Hirayama, M. Taki, M. Nakamura, T. Arata, Y. Yamamoto
Chem. Lett., 35, 834–835 (2006).
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Quantum mechanical hydrogen tunneling in bacterial copper amine oxidase reaction
T. Murakawa, T. Okajima, S. Kuroda, T. Nakamoto, M. Taki, Y. Yamamoto, H. Hayashi, K. Tanizawa
Biochem. Biophys. Res. Commun., 342, 414–423 (2006).
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Kinetic and structural studies on the catalytic role of the aspartic acid residue conserved in copper amine oxidase
Y.-C. Chiu, T. Okajima, T. Murakawa, M. Uchida, M. Taki, S. Hirota, M. Kim, H. Yamaguchi, Y. Kawano, N. Kamiya, S. Kuroda, H. Hayashi, Y. Yamamoto, K. Tanizawa
Biochemistry, 45, 4105–4120 (2006).
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Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C
S. Chatani, M. Nakamura, H. Akahane, N. Kohyama, M. Taki, T. Arata, Y. Yamamoto
Chem. Commun., , 1880–1882 (2005).
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Model complexes of the active site of galactose oxidase. Effects of the metal ion binding sites
M. Taki, H. Hattori, T. Osako, S. Nagatomo, M. Shiro, T. Kitagawa, S. Itoh
Inorg. Chim. Acta, 357, 3369–3381 (2004).
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Emission Ratiometric Imaging of Intracellular Zinc: Design of a Benzoxazole Fluorescent Sensor and Its Application in Two-Photon Microscopy
M. Taki, J.L. Wolford, T.V. O'Halloran
J. Am. Chem. Soc., 126, 712–713 (2004).
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Oxidation mechanism of phenols by dicopper-dioxygen (Cu2/O 2) complexes
T. Osako, K. Ohkubo, M. Taki, Y. Tachi, S. Fukuzumi, S. Itoh
J. Am. Chem. Soc., 125, 11027–11033 (2003).
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Fine-tuning of copper(I)-dioxygen reactivity by 2-(2-pyridyl)ethylamine bidentate ligands
M. Taki, S. Teramae, S. Nagatomo, Y. Tachi, T. Kitagawa, S. Itoh, S. Fukuzumi
J. Am. Chem. Soc., 124, 6367–6377 (2002).
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Oxo-transfer reaction from a bis(μ-oxo)dicopper(III) complex to sulfides
M. Taki, S. Itoh, S. Fukuzumi
J. Am. Chem. Soc., 124, 998–1002 (2002).
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Modulation of coordination chemistry in copper(I) complexes supported by bis[2-(2-pyridyl)ethyl]amine-based tridentate ligands
T. Osako, Y. Tachi, M. Taki, S. Fukuzumi, S. Itoh
Inorg. Chem., 40, 6604–6609 (2001).
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Oxygenation of phenols to catechols by a (μ-η2:η2-peroxo)dicopper(II) complex: Mechanistic insight into the phenolase activity of tyrosinase [1]
S. Itoh, H. Kumei, M. Taki, S. Nagatomo, T. Kitagawa, S. Fukuzumi
J. Am. Chem. Soc., 123, 6708–6709 (2001).
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C-H bond activation of external substrates with a bis(μ-oxo)dicopper(III) complex [2]
M. Taki, S. Itoh, S. Fukuzumi
J. Am. Chem. Soc., 123, 6203–6204 (2001).
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Model complexes for the active form of galactose oxidase. Physicochemical properties of Cu(II)- and Zn(II)-phenoxyl radical complexes
S. Itoh, M. Taki, H. Kumei, S. Takayama, S. Nagatomo, T. Kitagawa, N. Sakurada, R. Arakawa, S. Fukuzumi
Inorg. Chem., 39, 3708–3711 (2000).
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Active site models for galactose oxidase containing two different phenol groups
M. Taki, H. Kumei, S. Nagatomo, T. Kitagawa, S. Itoh, S. Fukuzumi
Inorg. Chim. Acta, 300-302, 622–632 (2000).
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Resonance Raman spectroscopy as a probe of the bis(μ-oxo)dicopper core
P.L. Holland, C.J. Cramer, E.C. Wilkinson, S. Mahapatra, K.R. Rodgers, S. Itoh, M. Taki, S. Fukuzumi, L. Que Jr., W.B. Tolman
J. Am. Chem. Soc., 122, 792–802 (2000).
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Aliphatic hydroxylation by a bis(μ-oxo)dicopper(III) complex
S. Itoh, M. Taki, H. Nakao, P.L. Holland, W.B. Tolman, L. Que Jr., S. Fukuzumi
Angew. Chem. Int. Ed., 39, 398–400 (2000).
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Hydrogen atom abstraction by Cu(II)- and Zn(II)-phenoxyl radical complexes, models for the active form of galactose oxidase
M. Taki, H. Kumei, S. Itoh, S. Fukuzumi
J. Inorg. Biochem., 78, 1–5 (2000).
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Oxidation of benzyl alcohol with Cu(II) and Zn(II) complexes of the phenoxyl radical as a model of the reaction of galactose oxidase
S. Itoh, M. Taki, S. Takayama, S. Nagatomo, T. Kitagawa, N. Sakurada, R. Arakawa, S. Fukuzumi
Angew. Chem. Int. Ed., 38, 2774–2776 (1999).