植物分子生理学研究室
Lab for Plant Molecular Physiology, Fac Appl Biol Sci, Gifu University
Introduction of LDSS analysis (3)
LDSS-positive elements are detected by looking at distribution profiles in a large set of promoter sequences.
Advantage of LDSS analysis over Gibbs Sampling and comparative genomics approaches:
* Sensitive detection of minor elements in the utilized promoter set (red)
* Extraction of single genome-specific information
* No need for microarray or ChIP-chip data
References
Clustering of DNA sequence in human promoters
FitzGerald PC, Shlyakhtenko A, Mir AA, Vinson C. Genome Res 14: 1562-1574, 2004 <PubMed>
Identification of plant promoter constituents by analysis of local distribution of short sequences
Yamamoto YY, Ichida H, Matsui M, Obokata J, Sakurai T, Satou M, Seki M, Shinozaki K, Abe T. BMC Genomics 8: 67, 2007 <PubMed>
Relative Position from TSS
Deduced promoter architecture
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